Doctoral Position on viscoelastic hydrogels for 3D mechanobiology and tissue repair

ETH Zurich seeks a doctoral researcher to develop dynamic covalent hydrogels for mechanobiology studies. This full-time, onsite role focuses on material synthesis and biological application within the Department of Mechanical and Process Engineering.

The successful candidate will join the Department of Mechanical and Process Engineering (D-MAVT) at ETH Zurich to investigate how matrix viscoelasticity influences biological processes. The primary objective is to create a library of dynamic covalent hydrogels that serve as designer extracellular matrix mimics, thereby uncovering key mechanistic roles in tissue repair and mechanobiology.

Responsibilities

• Create PEG- and hyaluronic acid-based dynamic covalent hydrogels using dynamic covalent cross-linking strategies.
• Produce and analyze material properties through rheological testing and nano-indentation techniques.
• Utilize customizable hydrogel scaffolds to investigate fundamental questions in mechanobiology.
• Support laboratory operations and educational activities, which may include supervising students, assisting with lectures, and leading practical sessions.

Requirements

• Hold a Master of Science degree in bioengineering, biomedical engineering, mechanical engineering, molecular health sciences, materials science, chemistry, or a closely related discipline.
• Demonstrate practical proficiency in polymer synthesis and the fabrication of hydrogels.
• Communicate effectively in English, both verbally and in writing.

Nice to have

• Hands-on experience with 3D cell culture systems and standard biological assays.
• Background in mechanical testing of soft materials, such as rheology or compression testing.
• Familiarity with live-cell imaging techniques and subsequent image analysis.

What the company offers

• Funding provided by the Swiss National Science Foundation.
• Employment is contingent upon acceptance into the Doctoral Program at ETH Zurich.

About the company

ETH Zurich stands as a worldwide leader in the fields of science and engineering. The university is situated in Zurich, an international hub known for its vibrant scientific community, rich cultural scene, and easy access to outdoor activities and other European cities.

• The institution is recognized globally for excellence in scientific research and engineering education.
• The location offers a high quality of life with diverse cultural, recreational, and professional opportunities.