Senior Principal Scientist - Proteomics

Novartis Pharma Schweiz AG seeks a Senior Principal Scientist in Proteomics for its Basel site. The position leads high-impact proteomics analyses across drug discovery programs, combining technical leadership with cross-functional collaboration.

This role is responsible for initiating, leading, and overseeing high-impact proteomics analyses across drug discovery programs, spanning from early research to translational studies involving patient samples. The scientist contributes to interdisciplinary research within a collaborative, matrixed environment, partnering across internal cross-functional teams and with external collaborators.

Responsibilities

• Lead and manage proteomics analyses throughout drug discovery programs, from early research to translational studies with patient samples.
• Collaborate within interdisciplinary research programs, working with internal cross-functional teams and external partners in a matrixed structure.
• Keep the proteomics platform current by monitoring technological advancements and aligning capabilities with project needs.
• Promote innovation in biomedical research by adopting advanced technologies and cross-disciplinary initiatives, including low-input and spatial proteomics.
• Mentor junior scientists, support project teams, and facilitate the work of direct and matrix reports.

Requirements

• PhD in biology, biochemistry, or a related field, with at least five years of academic experience in proteomics for biomedical research, or equivalent industry experience.
• Deep knowledge and hands-on experience with proteomics approaches and technologies, demonstrated by a strong publication record and contributions to the field.
• Strong data science skills with a solid understanding of biostatistical principles.
• Proven ability to lead cross-functional teams in a matrix environment.
• Collaborative and innovative mindset, with the ability to adapt quickly in a dynamic, multi-disciplinary research setting.
• Exceptional communication and presentation skills for multidisciplinary audiences.

Nice to have

• Experience with pathway analysis and multi-omics data integration, along with skills in Python and/or R.
• Expertise in spatial and low-input proteomics.

What the company offers

• Competitive benefits including insurance plans, retirement plans, wellbeing resources, and global recognition programs.
• Flexible and hybrid working options where possible.
• Minimum 14 weeks paid parental leave.
• Performance-based bonus depending on certain performance parameters.
• Long-term equity awards granted at group level may also be part of the package.

About the company

Novartis is committed to reimagining medicine together.

• Commitment to reimagining medicine together.