Senior Scientist 2, Chemical Development & Manufacturing

BioMarin Pharmaceutical Inc. (Swiss Office) seeks a Senior Scientist 2 for Chemical Development & Manufacturing to lead clinical programs and manage CDMO partnerships in a hybrid role based in Switzerland.

This position sits within the Chemical Development & Manufacturing group of the Drug Substance Technologies function. The incumbent serves as a Partner Team Lead, guiding clinical programs through Process Performance Qualification (PPQ) while overseeing CMC development for synthetic chemistry initiatives across Technical Operations.

Responsibilities

• Coordinate with Drug Substance modality teams, sister groups in TDS, and broader Technical Operations groups.
• Oversee active programs involving Contract Manufacturing and Development Organizations (CDMOs).
• Support group strategy, budget planning, monitoring, and overall program scheduling.
• Collaborate with technical teams to ensure enterprise-wide program timelines are met.
• Identify, evaluate, and assist in selecting new CDMO partners.
• Drive the strategy and performance of the CDMO network and internal functions.
• Anticipate scientific, business, and program challenges, solving problems cross-functionally.
• Manage the drafting and delivery of 3.2.S filing sections and address Health Authority questions.
• Make periodic in-person visits to other BioMarin and CDMO locations.
• Identify, evaluate, and implement new synthetic chemistry technologies.

Requirements

• Bachelor, Masters or PhD level in Chemistry or Chemical Engineering.
• Combined minimum of 9 years of related experience in synthetic molecule, drug substance development environments and CMC DS program management.
• Working knowledge of pharmaceutical regulatory requirements and solid cGMP skills.
• Excellent written and oral communication skills.
• Demonstrated capability at handling multiple programs and projects at one time.
• Agreement to work in a hybrid fashion, spending 2 days per week on average at the local BioMarin site.
• Travel of 20% – 30%.

Nice to have

• Experience in Oligonucleotide development and/or manufacture.
• Familiarity and/or working with ERP and quality documentation systems.
• Post-doctoral experience.
• Business, leadership or related training credentials.

About the company

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions. The company is guided by a purpose to develop medicines that make a profound impact on people’s lives. The role offers an opportunity to join an established, high functioning team with a growth mindset.

• BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions.
• The company is guided by a purpose to develop medicines that make a profound impact on people’s lives.
• The role offers an opportunity to join an established, high functioning team with a growth mindset.