Computational Biologist

Proxima Group AG seeks a Computational Biologist in Zürich to build an AI-driven drug discovery platform, focusing on protein interactions and therapeutic modalities.

The company is developing an AI-driven approach to drug discovery by making protein interactions programmable. This position focuses on building a leading platform for novel induced proximity therapeutic modalities, working closely with Computational Chemistry, Machine Learning, and Application Engineering teams.

Responsibilities

• Build large-scale data pipelines and develop pilot capabilities from scratch.
• Collaborate with internal teams and external partners to advance research projects through code, analyses, benchmarks, and optimization strategies.
• Incorporate biological insights into advanced AI and machine learning models designed for drug discovery.
• Validate and interpret computational predictions through close collaboration with experimental researchers.

Requirements

• MSc or PhD in computational biology, bioinformatics, or a closely related discipline.
• Combined academic and/or industrial background, with preference for biotech industry experience.
• Strong expertise in computational structural or systems biology.
• Proficient programming skills in Python, R, or similar languages.
• Proven experience in creating reproducible and scalable computational biology workflows.
• Background in designing and applying machine learning models.

Nice to have

• Familiarity with geometric deep learning, graph neural networks, protein language models, transformers, and representation learning.
• Prior exposure to drug discovery challenges.
• Experience with cloud-based infrastructure.
• Agile project management skills.

What the company offers

• Highly competitive salary packages.
• Company equity, ensuring every team member is a stakeholder.
• 401(k) retirement plan with company matching.
• Comprehensive medical, dental, and vision insurance (PPO with HSA & FSA options).
• 13 paid holidays plus unlimited PTO and sick time.
• Generous parental leave: 18 weeks fully paid for maternity leave and 6 weeks for paternity leave.
• In-office lunch provided five days a week.

About the company

The company values individuals who are driven to make an impact, possess deep intellectual curiosity, enjoy solving challenging problems, and have a track record of achievement.

• Values individuals who want to make an impact.
• Encourages deep intellectual curiosity.
• Focuses on solving challenging problems.
• Appreciates a track record of achievement.