RiSM Internship: PFAS-Free Analysis of Peptide APIs (Basel, 12 months)

Roche · Basel

Roche seeks an intern in Basel to support Analytical Development by researching and optimizing PFAS-free analytical methods for peptide APIs within a sustainable, science-driven environment.

This internship is situated within the Analytical Development & Quality Control team of Pharma Technical Development in Basel. The primary objective is to assist the department in evaluating and creating sustainable, PFAS-free alternative analytical methods for New Chemical Entities, with a specific focus on peptides.

Responsibilities

  • Perform an extensive literature review to identify current PFAS-free analytical techniques suitable for characterizing New Chemical Entities.
  • Engage in sustainable research initiatives aimed at substituting hazardous solvents and modifiers with eco-friendly, PFAS-free alternatives in standard workflows.
  • Contribute to the development and optimization of alternative RP-HPLC methods tailored for the characterization of New Chemical Entities.
  • Attend regular alignment meetings with supervisors to review project progress and address technical challenges.
  • Finalize the internship by writing a detailed report and presenting the findings to the scientific team.

Requirements

  • Currently enrolled in a university program or graduated within the last 12 months before the start date.
  • Background in Chemistry, Pharmaceutical Sciences, or Biochemistry is preferred.
  • Hands-on experience in a laboratory setting, including basic operation of HPLC/UHPLC and LC-MS systems.
  • Practical experience with New Chemical Entities, such as peptides or oligonucleotides, is ideal.
  • Proficiency in MS Office applications (Word, Excel, PowerPoint).

Nice to have

  • Strong proficiency in both English and German is considered a significant advantage.

What the company offers

  • Comprehensive onboarding and training covering SOPs, advanced analytical instrumentation, and industry-standard software.

About the company

Roche is a global healthcare company with more than 100,000 employees dedicated to advancing science to improve people's lives. The organization is committed to preventing, stopping, and curing diseases while ensuring access to healthcare for all. The workplace culture fosters personal expression, open dialogue, and genuine connections, where every employee is valued, accepted, and respected.

  • A culture that encourages personal expression and open dialogue.
  • A commitment to preventing, stopping, and curing diseases.
  • A global workforce of over 100,000 employees advancing science.
  • An environment where employees are valued, accepted, and respected.

How to apply

Documents to submit:

  • CV
  • Motivation Letter
  • Certificate of enrollment
  • RiSM task

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