GlycoEra seeks a Senior Scientist in Wädenswil to advance novel expression technology through hands-on fermentation and cell-culture process development, optimization, and scale-up.
This position focuses on pushing novel expression technology to the next level by combining deep scientific thinking with creative, hands-on experimentation. The successful candidate will drive the advancement of fermentation and cell-culture processes, translating insights into tangible process improvements.
Responsibilities
- Design and carry out upstream process-development studies with limited oversight.
- Convert literature findings into hypothesis-driven experiments that enhance processes.
- Identify and refine critical parameters that influence upstream performance.
- Utilize analytical methods to better understand organism physiology and fermentation outcomes.
- Operate bioreactors as part of the development workflow and assist with routine production tasks.
- Document, analyze, and present experimental results clearly.
- Perform core laboratory activities such as media preparation, shake-flask studies, bioreactor setup, process monitoring, inoculation, harvest, centrifugation, and sterile filtration.
- Adhere to SOPs and guidelines to maintain culture integrity, prevent contamination, and ensure compliance.
- Apply creative, engineering-driven thinking to improve the expression platform.
- Troubleshoot bottlenecks and propose innovative, scientifically grounded solutions.
- Collaborate with process development, analytical development, and protein sciences teams.
- Contribute to project planning, timelines, and risk assessments.
Requirements
- PhD in Biotechnology, Biochemical Engineering, Microbiology, or a related field.
- At least 5 years of relevant experience in fermentation or cell-culture process development.
- 3 years industry experience.
- Strong hands-on expertise with bioreactors, fermentation control systems, and scale-up principles.
- Experience with contamination-control strategies, operational risk assessment, and process monitoring.
- Solid understanding of bioprocess engineering fundamentals, metabolic principles, and cell physiology.
- Broad hands-on experience with mammalian cell culture platforms, including fed-batch and/or perfusion.
- Independent, proactive, and able to drive progress with minimal supervision.
- Willing to spend a considerable amount of time hands-on in the laboratory.
- Strong data analysis skills and familiarity with common bioprocess software tools.
- Creative, resourceful, and persistent in solving technical challenges.
- Clear communicator and collaborative team player.
Nice to have
- Experience with tech transfer activities.
- Experience with microbial expression systems.
About the company
GlycoEra is a company dedicated to developing novel expression technology, aiming to advance the field through innovative scientific approaches and hands-on experimentation.
How to apply
Documents to submit:
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