Student Internship in Analytical Development for Peptide Characterization with LC-MS (Basel, 9-12 months)

Roche seeks a student intern for a 9-12 month placement in Basel to develop LC-MS/MS methods for peptide characterization within the HST team.

This internship is situated within the Synthetic Molecule Analytical Development department (PTDC-A) under Global Technical Development (PTD). The candidate will join the specialized Hyphenated & Special Technologies (HST) team, which consists of more than 20 mass spectrometry experts, to support analytical development activities for synthetic molecules.

Responsibilities

• Create and optimize modern LC-MS/MS methods to measure the enantiomeric purity (D/L ratio) of amino acids found in synthetic peptides.
• Perform sample preparation tasks, including peptide hydrolysis, and conduct precise LC-MS/MS measurements.
• Manage, process, and interpret complex data generated by analytical mass spectrometry instruments.

Requirements

• Be a recent Master’s graduate or a student close to completing Master’s level studies.
• Hold an academic background in analytical chemistry or a related scientific discipline such as Chemistry, Biochemistry, Pharmacy, or Food Chemistry.
• Demonstrate strong theoretical knowledge and hands-on experience with analytical instruments, chromatographic separation methods, and sample preparation protocols.
• Possess business-level proficiency in English.
• Show strong problem-solving abilities and the capacity to work independently while collaborating effectively within a team.

Nice to have

• Knowledge of the German language.
• Previous practical experience using LC-MS analytics.
• A solid understanding of peptide and amino acid structures, along with familiarity with derivatization techniques or acid hydrolysis.

What the company offers

• Guidance and mentorship from experienced Roche scientists.
• Opportunities to gain hands-on expertise with state-of-the-art LC-MS techniques and advanced sample preparation methods.
• Professional experience working within an international pharmaceutical environment.

About the company

Roche employs more than 100,000 people worldwide who are dedicated to advancing science to improve human health. The company’s mission is to prevent, stop, and cure diseases while ensuring that everyone has access to healthcare. The workplace culture promotes personal expression, open dialogue, and genuine connections, ensuring that employees are valued, accepted, and respected.

• A global workforce of over 100,000 employees focused on advancing science.
• A mission centered on preventing, stopping, and curing diseases.
• A culture that values personal expression, open dialogue, and mutual respect.

How to apply

Documents to submit:

• CV
• Motivation letter
• Proof of enrollment or degree
• Certificate of mandatory internship